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Tilmaamaha ficilka ee fluconazole

Fluoxapyr waa carboxamidefungicidesay soo saartay BASF.Waxay leedahay waxqabadyo ka hortag iyo daaweyn wanaagsan.Waxaa loo isticmaalaa si looga hortago loona xakameeyo cudurrada fangas-ka ballaaran, ugu yaraan 26 nooc oo cudurrada fangas ah.Waxaa loo isticmaali karaa ku dhawaad ​​100 dalagga, sida dalagyada badarka, digirta, dalagyada saliidda, lawska, geedaha rummaanka iyo dhagaxa, khudradda xididka iyo digriiga, khudaarta miraha iyo suufka, caleen ama dawaynta abuurka.Fluoxafenamide waa ka hortag succinate dehydrogenase iyo fungicide aad u wanaagsan oo la sameeyay sanadihii ugu dambeeyay.
Tilmaamaha physicochemical ee fluconazole

Fluconazole Magaca Kiimikada: 3- (difluoromethyl) -1-methyl-N- (3′,4′,5′-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide, 3-(difluoro Methyl)-1- methyl-N- (3',4',5'-trifluorobiphenyl-2-yl) -1H-pyrazole-4-carboxamide;CAS No: 907204-31-3, Qaaciddada Molecular: C18H12F5N3O.Miisaanka unugyada: 381.31 g/mol.Fluoxapyr (nadiifinta 99.3%) waa caddaan ilaa beige adag, aan ur lahayn, dhibic dhalaalaysa 156.8 ℃, cufnaanta qaraabo (20℃) 1.42 g/ml, qudhuntaa qiyaastii 230 ℃, cadaadiska uumiga (qiyaasta): 2.7×10-9 Pa 20°C), 8.1×10-9 Pa (25°C);Joogtada Henry: 3.028×10-7 Pa·m3/mol.Solubility (20℃): biyaha 3.88 mg/L (pH 5.84), 3.78 mg/L (pH 4.01), 3.44 mg/L (pH 7.00), 3.84 mg/L (pH 9.00);dareeraha organic (nadiifinta farsamada 99.2)%) (g / L, 20 ℃): acetone> 250, acetonitrile 167.6 ± 0.2, dichloromethane 146.1 ± 0.3, ethyl acetate 123.3 ± 0.2, methanol 53.4 ± 0.0. octanol 4.69 ± 0.1, n-heptane 0.106 ± 0.001.n-octanol-water partition coefficient (20°C): Log-qoyseedka biyaha Kow 3.08, log Kow 3.09 (pH 4), log Kow 3.13 (pH 7), log Kow 3.09 (pH 9), log celceliska Kow (3.10±0.02). ) .Ku xasiloon xal aqueous at pH 4, 5, 7, 9 hoos xaaladaha mugdiga iyo naxaas ah.Iftiinku waa deggan yahay.

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Sunta Fluoxafen

Sunta afka ba'an ee jiirka (haweenka) ee daawada asalka ah ee fluconazole: LD50≥2,000 mg/kg, sunta maqaarka daran ee jiirka (lab iyo dheddig): LD50>2,000 mg/kg, sunta neefsashada ba'an ee jiirka (lab iyo dheddig) : LC50>5.1 mg/L;xanaaq yar indhaha bakaylaha iyo maqaarka bakaylaha;dareen la'aan maqaarka doofaarka Guinea.Ma jiro kansar, ma laha teratogenicity, wax saameyn ah oo ku yimaada taranka ma jiro, ma jiro genotoxicity, neurotoxicity iyo immunotoxicity.
Sunta degdega ah ee shimbiraha LD50 ~ 2,000 mg/kg, sunta daran ee Daphnia 6.78 mg/L (48 h), suntan ba'an ee kalluunka (96 h) LC50 0.546 mg / L, sunta daran ee qulqulka biyaha (48 h) ) 780 mg/L, suntan ba'an ee algae (72 h) EC50 0.70 mg/L, sunta xidhiidhka ba'an ee shinnida (48 h) LD50>100 μg/shini, suntan afka ba'an ee shinnida (48 h) LD50>110.9 μg/shini, Sunta degdega ah ee gooryaanka dhulka waa LC50>1,000 mg/kg (14 maalmood).Xogta kore, waxaa laga arki karaa in Fluoxafen ay sun u tahay noolaha biyaha oo ay ku yar tahay sunta noolaha kale ee faa'iidada leh.

Farsamaynta ficilka fluoxafen

Fluoxafenamide waa succinate dehydrogenase inhibitor, kaas oo ku shaqeeya succinate dehydrogenase ee silsiladda neefsiga ee mitochondrial II si ay u joojiso hawsheeda, taas oo ka hortagaysa biqilka fangas fangas kudka, koritaanka tuubooyinka jeermiska iyo mycelium.

Walxaha xakamaynta Fluconazole

Fluoxamid waa mid aad waxtar u leh, baaxad ballaaran, waara, xul ah, leh habdhismeed aad u wanaagsan, waxayna u adkaysataa nabaad guurka roobka.Waxay si wax ku ool ah u xakameyn kartaa badarka, soybeans, galleyda, abuur kufsiga, geedaha miraha, khudaarta, iyo dabocase sonkorta iyada oo loo marayo daawaynta caleenta iyo abuurka., lawska, suufka, cawska iyo dalagyada khaaska ah, iwm, sida badarka, soybeans, geedaha khudaarta iyo khudaarta ay sababaan Concha, Botrytis cinerea, caarada budada, Cercospora, Puccinia, Rhizoctonia, Sclerotium Cudurada ay keento fangaska godka, botrytis cinerea, miridhku. , caarada budada ah ee caleenta, suufka, cudurada gabbaldayaha iyo kufsiga ee ay keento Alternaria, iwm

Fluoxafen waxay leedahay la qabsi xooggan, waxaana jira noocyo badan oo alaabooyin isku dhafan ah.Adexar (fluconazole + epoxiconazole) waxaa loo isticmaalaa qamadiga, shaciir, triticale, galley iyo miro si loo xakameeyo caariyaysi budada ah, xariijimaha caleenta, xariijimaha xariijimaha iyo miridhka caleenta.Priaxor (flufenapyr + pyraclostrobin) waxay ka diiwaan gashan tahay Maraykanka soybean, yaanyo, baradhada iyo dalagyada kale ee beeraha, waxayna leedahay saameyn gaar ah oo ku saabsan xakamaynta barta brown soybean (Septoria glycines);Orkestra SC (flufenapyr + Pyraclostrobin) waxay ka diiwaan gashan tahay Brazil digirta, liinta, baradhada, basasha, karootada, tufaaxa, cambe, qaraha, qajaarka, basbaaska dawan, yaanyada, canola, lawska, digirta kelyaha, ubaxa gabbaldayaha, hadhuudhka, galleyda, sarreenka iyo ubax ( Chrysanthemum iyo Rose), iwm, waxay xakameyn karaan miridhku soybean Asian, kor u photosynthesis ee dalagyada, iyo in loo isticmaalo maaraynta iska caabinta cudurada.Priaxor D (flufenapyr + pyraclostrobin + tetraflufenazole) waxay ka diiwaan gashan tahay Maraykanka ka hortagga iyo xakamaynta barta cawlan soybean ee u adkaysata fungicides methoxyacrylate.Wakiilka daaweynta abuurka Obvius (flufenapyr + pyraclostrobin + metalaxyl) wuxuu ka diiwaan gashan yahay Mareykanka wuxuuna xakameyn karaa noocyo kala duwan oo cudurada seedling ah oo dalagyo badan ah.

The succinate dehydrogenase inhibitor fungicides ayaa si degdeg ah u koray sannadihii la soo dhaafay, iyo fluoxamid waa sheyga ugu horreeya ee noocan oo kale ah fungicides, mahad leh hufnaan sare, spectrum ballaaran, dhaqdhaqaaqa nidaamka, ku haboon noocyo kala duwan oo dalagyada iyo sifooyinka kale Gaar ahaan, joogto ah. horumarinta wax soo saarka ay ka kooban yahay ayaa balaariyay xakamaynta spectrum iyo baaxadda dalagga codsatay, oo waxay noqotay luul dhalaalaya suuqa fungicides.

 

 

 


Waqtiga boostada: Jul-18-2022